High Yield Reviews
Download this open access article from the American Heart Association for full details of antibody mediated rejection
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Immediately or within hours after transplant
Platelet aggregates in vessels
Eventually, PMNs come in and are seen
Lymphocytes, Macrophages and Eosinophils
DDx of Eos: Drug rxn, toxoplasmosis, CMV
NO Neutrophils (PMNs)
(can be seen with ischemia, antibody-mediated rejection, or infection)
NO plasma cells!!
(if present = Quilty lesion or PTLD)
PMNs near capillaries
IgG, IgM, IgA, C3d, C4d, C1q