Fat Necrosis (Breast)
Phagocytosis of necrotic adipose cells
Most common cause is trauma (MVC etc.)
Can be seen with duct ectasia that has ruptured (may have apocrine metaplasia present)
Trauma to breast then patient has a localized, firm area with eventual scarring & calcifications.
Consists of necrotic adipocytes, fibrosis and inflammation
Irregular steatocytes with loss of peripheral nuclei
Pink amorphous necrotic material/debris
Foamy (lipid-laden) macrophages
+/- Foreign body giant cells
BEWARE: Reactive fibroblasts and reactive endothelial cells can look ugly and can be confused with carcinoma!!