Granulomatous Mastitis

(Idiopathic) Granulomatous inflammation

General Information:

  • Most granulomatous inflammatory lesions of the breast are idiopathic.

  • Often clinically presents as a mass lesion in young females with a history of recent pregnancy.

Histologic findings:

  • Granulomatous inflammation admixed with neutrophils

  • A few granulomas show central neutrophilic infiltrate (microabscess)

  • Caseous necrosis is NOT seen

DDx: Must exclude other causes of granulomatous inflammation (TB, sarcoid, fungal infection etc)

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