Updated: Aug 16, 2018


  • Gynecomastia simply refers to an increased amount of breast tissue in a male

  • Uncommon condition.

  • A minority of cases are associated with BRCA2 mutation.

Clinical picture

1. Young boy with enlarged breasts (can be unilateral).

  • May be idiopathic & resolve spontaneously. Some require surgery

2. Old man with enlarged breasts

  • Due to high estrogen levels:

  1. Cirrhosis (decreased hepatic clearance of estrogen)

  2. Some drugs

  3. Klinefelter syndrome (XXY)

  4. Leydig cell tumor of testis

3. Other

  • Can be seen in hyperthyroidism, prolactinomas, or AIDS patients on HAART therapy


  • Abundant collagenous dense stroma with only small ductular tissue with loss of lobular units

  • End ducts without lobules

  • Can have well or poorly defined borders

  • Can see ductal epithelial hyperplasia or prominent periductular edema

  • looks similar to desmoplastic stromal reaction or pseudoangiomatous stromal hyperplasia

Sign Out

Breast, [Right/Left], mammoplasty:

- Benign breast tissue, (weight) g.

  • Facebook - Black Circle
  • Twitter - Black Circle
  • Pinterest - Black Circle


These posts contain high yield information collected from various educational resources including textbooks, journal articles, educational websites and more. They are intended for educational use only and should NOT be taken as medical advice. I strongly believe the spreading of knowledge and depth of learned information should be encouraged in today's society rather than coveted. Membership is required to view these posts  and should be used solely for educational purposes only.